Saint Jerome is best known as the translator of the Latin Vulgate Bible. In medieval times, Jerome was declared to be one of the four great Doctors of the Latin Church. The Council of Trent spoke of him as “the greatest doctor in the explanation of Holy Scripture.” Jerome’s Commentary on Isaiah is his longest extant work and considered by many to be his magnum opus. Respected scholar Thomas P. Scheck has offered the English speaking world the first translation of Commentary on Isaiah, as well as an introduction to Saint Jerome’s life and work and translations of Origen’s homilies on Isaiah. The work is heavily indebted to the Greek exegetical tradition, especially Origen.